Reflection on the teaching of laboratory interns under the corona virus disease 2019 / 中华医学教育探索杂志

In the new or variant acute respiratory infectious diseases, as a result of the not fully discovered ways to control the infection as well as the not fully defined pathogenicity of pathogens, there is still a greater risk of infection for the laboratory front-line staff who are in close contact with pathogen samples. Therefore, the psychological status, biological safety, and work quality of the interns in the laboratory are also main concerns of the teaching hospitals in the epidemic prevention and control work. In view of the problems exposed in the epidemic situation of viral respiratory infectious diseases, this paper analyzes the influence of the whole process of the test on the test results and carries out the process control, aiming at enhancing the interns' ability to resist pressure, improving the students' awareness of biological safety, promoting the interns' comprehensive analysis ability and the formation of clinical critical thinking, and providing reference for the training qualified medical laboratory professionals.

Proposal for detection of 2019-nCoV nucleic acid in clinical laboratories / 中华检验医学杂志

In December, the outbreak of a novel coronavirus (2019-nCoV) in Wuhan, China, has attracted extensive global attention. On January 20, 2020,the Chinese health authorities upgraded the coronavirus to a Class B infectious disease in the Law of the People's Republic of China on the Prevention and Treatment of Infectious Diseases, and considered it as Class A infectious diseases in disease control and prevention. On January 22, 2020, the 2019-nCoV nucleic acid detection test was listed as the diagnostic criteria in the "guidelines for diagnosis and treatment of pneumonia due to 2019-nCoV (Trial Version 2)" . Therefore, standardizing the operation process of the 2019-nCoV nucleic acid detection in clinical laboratories has become a top priority. It is of paramount importance to establish standard protocols for detection of the 2019-nCoV nucleic acids in clinical laboratories to improve the reliability of the results and ensure the biosafety of laboratory personnel.

Biosafety Consensus for 2019 Novel Coronavirus Pneumonia in Clinical Laboratory / 中华检验医学杂志

With the outbreak and spread of the 2019 Novel Coronavirus pneumonia, laboratory biosafety has become increasingly prominent. The Society of Laboratory Medicine of Chinese Medical Association formulates this guideline with reference to Chinese National Recommendations and relevant documents. From the perspectives of Microbiology, Epidemiology, Case Definition, Safety Principles, Personal Precaution, Specimen Collection, Specimen Transport, Specimen Handling, Analysis, Post-Analysis and Emergencies, this guideline gives recommendations on biosafety precaution and biosafety protection. We hope that it can be practically implemented and continuously improved to ensure laboratory safety.

Analysis and future perspectives of the grants funded by National Natural Science Foundation of China on tumor biomarker research in laboratory medicine from 2010 to 2018 / 中华检验医学杂志

To summarize the projects granted by National Natural Science Foundation of China related to tumor biomarkers in laboratory medicine from 2010 to 2018. The projects are categorized and analyzed according to tumor classification, biochemical properties of biomarkers. What′s more, characters of granted projects of tumor biomarkers in recent 9 years are summarized and development trends are pointed out.

The role of laboratory developed tests in the development of precision medicine and clinical experimental diagnosis / 中华检验医学杂志

The modern laboratory developed tests (LDTs) plays a very important role in the development of precision medicine and clinical laboratory diagnosis. The perfect LDTs inspection platform not only requires strict quality control system and management standards, but also requires technical support from high-end professional teams. By combing the development process of LDTs, this paper discusses the significance of developing LDTs in the context of precision medicine, the positive role played by the development of laboratory medicine and the cultivation of laboratory talents, and how to effectively develop LDTs.

Analysis and future perspectives of the grants funded by National Natural Science Foundation of China on tumor biomarker research in laboratory medicine from 2010 to 2018 / 中华检验医学杂志

To summarize the projects granted by National Natural Science Foundation of China related to tumor biomarkers in laboratory medicine from 2010 to 2018. The projects are categorized and analyzed according to tumor classification, biochemical properties of biomarkers. What's more, characters of granted projects of tumor biomarkers in recent 9 years are summarized and development trends are pointed out.

The role of laboratory developed tests in the development of precision medicine and clinical experimental diagnosis / 中华检验医学杂志

The modern laboratory developed tests (LDTs) plays a very important role in the development of precision medicine and clinical laboratory diagnosis. The perfect LDTs inspection platform not only requires strict quality control system and management standards, but also requires technical support from high-end professional teams. By combing the development process of LDTs, this paper discusses the significance of developing LDTs in the context of precision medicine, the positive role played by the development of laboratory medicine and the cultivation of laboratory talents, and how to effectively develop LDTs.

Strategies and prospects for real world study in laboratory medicine / 中华检验医学杂志

Real world study has attracted more and more researchers' attention because of the evidence obtained from real clinical practice. With the development of big data in laboratory medicine and the needs for translational studies for diagnostic markers, the concept of real world study has also been introduced in laboratory medicine. This article presents a preliminary discussion on the opportunities and requirements for the real world study in the development of laboratory medicine, and on how the researchers conduct real world study.

Machine learning empowering laboratory medicine / 中华检验医学杂志

Traditional data storage strategy has not capacity to meet analytical needs of medical big data possessing with mixed structure and high-dimensional features. Machine learning based on algorithms that generate models in the data is becoming an innovative source of intelligent data analysis technology in computer simulation of human learning. This paper gives an introduction to the development of machine learning and its current background of medical big data. Emphases are placed on applications of machine learning in the medical image recognition, automated validation for test reports, Chinese medical language processing and computer-aided diagnosis. The opportunities and challenges to the development of laboratory medicine which taken from machine learning worth focusing.(Chin J Lab Med, 2018, 41: 627-630)

Analysis of projects appliation and grant funding in the field of laboratory medicine from National Natural Science Foundation of China during 2014-2017 / 中华检验医学杂志

At present , laboratory medicine has become one of the fastest growing subjects in the field of medicine.The development of laboratory medicine directly led to the improvement of diagnosis and the increase of test methods in clinic .The data of project applications and grants of the National Natural Science Foundation of China in the field of laboratory medicine from 2014 to 2017 were reviewed and summarized.The future prospect was also analyzed to provide references for related researchers in this field .

Practice and exploration of the laboratory medicine interns and training in hospital / 中华检验医学杂志

The clinical laboratory department practice in hospital is very important in the teaching process of medical laboratory science and medical laboratory technology science .It is the transition link of guiding the students to go to the clinical job .This paper analyzes the problems and challenges in the process of clinical teaching and management of the trainees majored in medical laboratory science and medical laboratory technology science .Then summarizes the countermeasures to effectively cultivate these trainees , including setting up a teaching group , doing the overall quality control for the process of practice teaching using ISO15189 quality control methods for reference , establishing the evaluation mechanism for both trainees and tutors , founding virtual laboratory to improve the teaching effect of morphology , strengthening the consciousness of quality control , expanding the professional vision of interns and strengthening the cultivation of the scientific research ability of interns .

Repetition of biochemistry tests in a laboratory of public hospital in southwest of Bahia, Brazil, and associated cost / Repetição de exames de bioquímica no laboratório de um hospital público do sudoeste da Bahia, Brasil, e custo associado

ABSTRACT Introduction: Test repetitions are an age-old practice common to clinical laboratories used primarily for confirmation of results. However, knowing the history of patients, the repetitions become avoidable. They impair the time to release results, increase input consumption, and cost of services. Objectives: to evaluate the difference between the results of the laboratory tests repetitions and the expenditure generated by each additional test. Materials and methods: Data from repeated tests from September to November 2015 were used in the laboratory of a public hospital in the state of Bahia, Brazil. The classification of necessary or unnecessary repetition of these tests was performed according to international criteria, with subsequent cost estimation. Results: A total of 1,350 samples were analyzed, with a total of 1,429 repetitions; 1,162 (81.31%) were classified as unnecessary repetitions, generating an additional cost of R$ 1,198.00 to the service. The repetitions that made up the study generated a cost of R$ 1,488.61, the expense should be only R$ 290.61, an increase of 80.47%, an estimated annual impact of R$ 4,792.00. In addition to the impact on cost, the impact on turnaround time was evident, which consequently affects the speed in patient care. Conclusion: It was observed that most of the repetitions performed in the laboratory were classified as unnecessary when evaluated by the criteria used. These repetitions generated a potentially avoidable laboratory cost increase, negatively impacting the time to release the results.

RESUMO Introdução: A repetição de exames é uma prática antiga comum aos laboratórios clínicos, usada basicamente para confirmação de resultados. No entanto, ao conhecer a história dos pacientes, as repetições tornam-se evitáveis. Elas prejudicam o tempo de liberação de resultados, aumentam consumo de insumos e geram custo aos serviços. Objetivos: Avaliar a diferença entre os resultados das repetições de exames laboratoriais e o dispêndio gerado por cada teste adicional. Materiais e métodos: Foram utilizados dados de exames repetidos de setembro a novembro de 2015 no laboratório de um hospital público do estado da Bahia, Brasil. Procedeu-se a classificação de repetição necessária ou desnecessária desses exames seguindo critérios internacionais, com posterior estimativa de custo. Resultados: Um total de 1.350 amostras foram analisadas, com 1.429 repetições ao todo; 1.162 (81,31%) foram classificadas como repetições desnecessárias, gerando um custo adicional ao serviço no valor de R$ 1.198,00. As repetições que compuseram o estudo geraram um custo de R$ 1.488,61, o gasto deveria ser de apenas R$ 290,61, ou seja, um acréscimo de 80,47%, um impacto anual estimado em R$ 4.792,00. Além do impacto no custo, ficou evidente o impacto no tempo de resposta, o que consequentemente afeta a celeridade na assistência aos pacientes. Conclusão: Observou-se que a maioria das repetições realizadas no laboratório foi classificada como desnecessária quando avaliada pelos critérios utilizados. Essas repetições geraram ao serviço um acréscimo de custo laboratorial potencialmente evitável, impactando negativamente no tempo para liberação dos resultados.

Exploration of flipped classroom model in the medical laboratory English class / 中华检验医学杂志

Specialty English of Medical Laboratory is a comprehensive and overlapping discipline and plays a major role in multiple medical courses, including Life Science, Clinical Medicine and Laboratory Medicine.However, its teaching practices are limited due to the extensive contents, scattered basic knowledge points, complexities of language learning processes and high demanding of sophisticated teaching skills.Since internet technology′s breakout and the web-based education expanding in the past decade, personalized flipped classroom has drawn considerable attention in the education field and became a hop-spot in teaching practice system.In the present study, the concepts of flipped classroom and basic characteristics of Specialty English of Medical Laboratory were elaborated, as well as the reconstructing teaching processes, exploring the concrete plan for teachers and students in undergraduate program.

“Big Data” in laboratory medicine,are we ready? / 中华检验医学杂志

“Big Data” gradually enters the field of Laboratory Medicine , there are some cases for clinical application of “Big Data”, such as quality control , reference interval , nutritional status and epidemiological investigation.There are also many challenges , such as experimental design , data accessect.Big Data mining needs more wisdom , more efforts.

Opportunities and challenges for the laboratory medicine in the era of precision medicine / 中华检验医学杂志

Precision medicine is an emerging approach for disease treatment and prevention , which attempts to explore the effective means for protecting human health by synthetical consideration of individual variability in genes , environment and life style.Precision medicine has the prominent property of multidisciplinary intercrossing and fusion , the development of which claims rapid clinical application of advanced technology in the research of basic medical science.What kind of development opportunities are laboratory medicine confronted with under the novel medical mode? How can laboratory medicine and its researchers do to seize these opportunities and meet the challenges of precision medicine ? These questions are preliminary discussed in this paper.

Construction of curriculum system of clinical laboratory medicine based on requirements of society / 中华医学教育探索杂志

The adjustment of Laboratory Medicine to the first class subject is both challenges and opportunities. In order to meet the requirements of the modern laboratory medicine on the improved knowl-edge and skill, Weifang Medical University sets a goal of cultivatinghigh-qualified and applicative profes-sional personnel of Laboratory Medicine Science. To realize that, we build a new curriculum system with features of Medical Laboratory Science, including the theoretical curriculum system and the practical teach-ing system. The theoretical curriculum system breaks the traditional framework of the old curriculum which designed according to the discipline category, builds a new curriculum system of platform and module, scientifically integrates the basic course group in clinical laboratory medicine, and adds the course of clinical examination skills with its own professional characteristics. In the practical teaching system, we focus on the cultivation of practice ability and innovation ability, encourage the students to go to the hospital and company earlier, and promote the integration of production, teaching and research in various approaches.

Molecular diagnosis in China：present status and challenges ahead / 中华检验医学杂志

Molecular diagnosis is rapidly developed in recent years , mainly applicated in the diagnosis of hereditary disease , infectious pathogens, tumor susceptibility and molecular typing , companion diagnosis and prognosis assessment , playing more and more important role in many diseases diagnosis and treatment.Molecular diagnosis was developed from the eighties of the last century in our country .Nowadays, the mainly applied technologies in the clinical laboratory include fluorescence in situ hybridization , quantitative PCR, microarray and DNA sequencing. These molecular technologies make up for the insufficiency of routine testing and take up a central role in the development of modern laboratory medicine . With the continuous development in transformation research of molecular technology recent years , there will be more molecular diagnostic techniques applied in clinicaldiagnosis in the future .But it still exists some drawbacks in the performance of molecular diagnosis in our country according to the current situation , such as imbalanced regional development , mismatched policies, non-standardized laboratory construction , deficiency of quality control and supervision , etc., which requires the joint effort of the government , hospital, professional association and clinical laboratory itself to promote the healthy and orderly development of molecular diagnosis.

Medical laboratory science and nursing students' perception of academic learning environment in a Philippine university using Dundee Ready Educational Environment Measure (DREEM) / 보건의료교육평가

PURPOSE: This study aimed to compare the perception of the academic learning environment between medical laboratory science students and nursing students at Saint Louis University, Baguio City, Philippines. METHODS: A cross-sectional survey research design was used to measure the perceptions of the participants. A total of 341 students from the Department of Medical Laboratory Science, School of Natural Sciences, and the School of Nursing answered the Dundee Ready Education Environment Measure (DREEM) instrument from April to May 2016. Responses were compared according to course of study, gender, and year level. RESULTS: The total mean DREEM scores of the medical laboratory science students and nursing students did not differ significantly when grouped according to course of study, gender, or year level. Medical laboratory science students had significantly lower mean scores in the sub-domains 'perception of learning' and 'perception of teaching.' Male medical laboratory science students had significantly lower mean scores in the sub-domain 'perception of learning' among second year students. Medical laboratory science students had significantly lower mean scores in the sub-domain 'perception of learning.' Nursing students identified 7 problem areas, most of which were related to their instructors. CONCLUSION: Medical laboratory science and nursing students viewed their academic learning environment as 'more positive than negative.' However, the relationship of the nursing instructors to their students needs improvement.

Quality indicators in clinical laboratories：past, status quo and future / 中华检验医学杂志

In recent years , with the development of error theory and the requirements of the international accreditation bodies , the quality indicators ( QIs) have become one of the important tools in the laboratory quality management .To explore the evolution and origin of QIs , the status and the future of QIs will be helpful for us to understand and to use the QIs .

Potential application of data mining in laboratory medicine / 中华检验医学杂志

A lot of important information were hidden in mass LIS data.Data mining technology can find useful data from multiple dimensions,providing information support for clinical diagnosis and treatment.This paper described the newly gained features of the laboratory medicine in the era of big data and analyzed the potential application of data mining in laboratory medicine.